Clinical Controlled Trials
Amy L. McKenziea, Shaminie J. Athinarayananb, Michelle R. Van Tieghem, Brittanie M. Volk, Caroline G.P. Roberts, Rebecca N. Adams, Jeff S. Volek, Stephen D. Phinney, Sarah J. Hallberg; 2024: 5-Year effects of a novel continuous remote care model with carbohydrate-restricted nutrition therapy including nutritional ketosis in type 2 diabetes: An extension study
Athinarayanan, S.J., Vantieghem, M., McKenzie, A.L., Hallberg, S., Roberts, C.G., Volk, B.M., Adams, R.N., Ratner, R.E., Volek, J. and Phinney, S., 2022. 832-P: Five-Year weight and glycemic outcomes following a very-low-carbohydrate intervention including nutritional ketosis in patients with type 2 diabetes. Diabetes, 71(Supplement_1).
Hallberg, S.J., McKenzie, A.L., Williams, P.T., Bhanpuri, N.H., Peters, A.L., Campbell, W.W., Hazbun, T.L., Volk, B.M., McCarter, J.P., Phinney, S.D. and Volek, J.S., 2018. Effectiveness and safety of a novel care model for the management of type 2 diabetes at 1 year: an open-label, non-randomized, controlled study. Diabetes Therapy, 9(2), pp.583-612.
Chen C-Y, Huang W-S, Chen H-C, et al. Effect of a 90 g/day low-carbohydrate
diet on glycaemic control, small, dense low-density lipoprotein and carotid intima-
media thickness in type 2 diabetic patients: An 18-month randomised controlled
trial. PLOS ONE. 2020;15(10):e0240158. doi:10.1371/journal.pone.0240158
McKenzie A, Athinarayanan S, Adams R, Volek J, Phinney S, Hallberg S. SUN-
LB113 A Continuous Remote Care Intervention Utilizing Carbohydrate Restriction
Including Nutritional Ketosis Improves Markers of Metabolic Risk and Reduces
Diabetes Medication Use in Patients With Type 2 Diabetes Over 3.5 Years. J
Endocr Soc. 2020;4(Supplement_1). doi:10.1210/jendso/bvaa046.2302 (5 Year
Data https://doi.org/10.2337/db22-832-P )
Thomsen MN, Skytte MJ, Astrup A, et al. The clinical effects of a carbohydrate-
reduced high-protein diet on glycaemic variability in metformin-treated patients
with type 2 diabetes mellitus: A randomised controlled study. Clinical Nutrition
ESPEN. Published online August 1, 2020. doi:10.1016/j.clnesp.2020.07.002
Govers E, Otten A, Schuiling B, Bouwman W, Visscher T. Effectiveness of the 6 ×
6 Dieet® in Obese DMT2 Patients Effectiveness of a Very Low Carbohydrate
Ketogenic Diet Compared to a Low Carbohydrate and Energy-Restricted Diet in
Overweight/Obese Type 2 Diabetes Patients. September 2019.
doi:10.16966/2380-548X.158
Tay J, Thompson CH, Luscombe-Marsh ND, et al. Effects of an energy-restricted
low-carbohydrate, high unsaturated fat/low saturated fat diet versus a high-
carbohydrate, low-fat diet in type 2 diabetes: A 2-year randomized clinical trial.
Diabetes Obes Metab. 2018;20(4):858-871. doi:10.1111/dom.13164